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ISSN 0973 - 0958
Different effects of probiotic species/strains
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NUTRITION IN CHILDREN
DIFFERENT EFFECTS OF PROBIOTIC SPECIES/STRAINS ON INFECTIONS IN PRESCHOOL CHILDREN: A DOUBLE-BLIND, RANDOMIZED, CONTROLLED STUDY
Source: Vaccine. 2009 Feb 11;27(7):1073-9.
Infectious diseases are the most significant illnesses for children under age 5, particularly for those attending preschool. It has been proven that children with mild diarrhea who consumed the combination of L. rhamnosus and L. reuteri experienced a reduction in the duration of the diarrhea. A study of 6- and 36-month old children afflicted with rotavirus gastroenteritis showed that L. reuteri significantly shortened the duration of diarrhea. It has been observed that several strains of probiotics have positive influences on non-specific stimulation of the host's immunity, although the molecular mechanism has not been elucidated. Many probiotics are capable of preventing respiratory infections and reducing their severity . Also, it was reported that mitigation or prevention of pediatric infectious disease occurred when children in day care centers ingested Lactobacillus. aim of this double-blind, randomized, controlled study was to compare the efficacy of three different probiotics?Lactobacillus casei rhamnosus, Lactobacillus rhamnosus T cell-1 and a multiple probiotic during short (3 months) and long term intervention (7 months). Among the 986 children who completed the study, 193 were in the control group, 285 were in the L. casei rhamnosus group, 222 were in the L. rhamnosus T cell-1 group, and 286 were in the multiple probiotic group. The investigated parameters were incidences of all pediatric diseases, bacterial infections, viral infections, gastrointestinal infections, and respiratory infections.
Results: Preschoolers' incidences of all pediatric diseases increased after entering the day care center in every group compared with the baseline period. Preschoolers who received probiotic treatment experienced a decline in physician visits, although this was statistically insignificant between the groups during the intervention period. The incidence of bacterial infection in the L. casei rhamnosus group and L. rhamnosus T cell-1 group showed a significant decrease in bacterial infection as compared to the control group). No significant differences in the incidence of bacterial infection were observed in the multiple probiotic and control groups. The L. casei rhamnosus probiotic reduced respiratory infections, but multispecies probiotic supplementation significantly reduced gastrointestinal disease.
Conclusion: Probiotics may be useful in preventing viral and bacterial infectious diseases in preschoolers.
Infectious diseases are the most significant illnesses for children under age 5, particularly for those attending preschool. It has been proven that children with mild diarrhea who consumed the combination of L. rhamnosus and L. reuteri experienced a reduction in the duration of the diarrhea. A study of 6- and 36-month old children afflicted with rotavirus gastroenteritis showed that L. reuteri significantly shortened the duration of diarrhea. It has been observed that several strains of probiotics have positive influences on non-specific stimulation of the host's immunity, although the molecular mechanism has not been elucidated. Many probiotics are capable of preventing respiratory infections and reducing their severity . Also, it was reported that mitigation or prevention of pediatric infectious disease occurred when children in day care centers ingested Lactobacillus. aim of this double-blind, randomized, controlled study was to compare the efficacy of three different probiotics?Lactobacillus casei rhamnosus, Lactobacillus rhamnosus T cell-1 and a multiple probiotic during short (3 months) and long term intervention (7 months). Among the 986 children who completed the study, 193 were in the control group, 285 were in the L. casei rhamnosus group, 222 were in the L. rhamnosus T cell-1 group, and 286 were in the multiple probiotic group. The investigated parameters were incidences of all pediatric diseases, bacterial infections, viral infections, gastrointestinal infections, and respiratory infections.
Results: Preschoolers' incidences of all pediatric diseases increased after entering the day care center in every group compared with the baseline period. Preschoolers who received probiotic treatment experienced a decline in physician visits, although this was statistically insignificant between the groups during the intervention period. The incidence of bacterial infection in the L. casei rhamnosus group and L. rhamnosus T cell-1 group showed a significant decrease in bacterial infection as compared to the control group). No significant differences in the incidence of bacterial infection were observed in the multiple probiotic and control groups. The L. casei rhamnosus probiotic reduced respiratory infections, but multispecies probiotic supplementation significantly reduced gastrointestinal disease.
Conclusion: Probiotics may be useful in preventing viral and bacterial infectious diseases in preschoolers.
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